Lactobacillus brevis SBC8803 and Neuroprotection Against Dopamine Neuronal Loss

• Heat-killed Lactobacillus murinus confers neuroprotection against dopamine neuronal loss by targeting NLRP3 inflammasome.

  • 2022-11-23
  • Bioengineering & translational medicine 8(2)
  • • Hong-Xia Fan
    • Shuo Sheng
    • Dai-Di Li
    • Jing-Jie Li
    • Guo-Qing Wang
    • Feng Zhang

  • PubMed: 36925673
  • DOI: 10.1002/btm2.10455

  2 Insights on

  • Neuroprotection Against Dopamine Neuronal Loss

  • Low evidence

  heat-killed L. murinus ameliorated 6-hydroxydopamine-induced motor dysfunctions and loss of substantia nigra DA neurons

  Effect

  Beneficial

  Effect size

  Moderate