Lactobacillus brevis SBC8803 and Reduced Airway Hyperresponsiveness

• Oral administration of heat-inactivated Lactobacillus plantarum K37 modulated airway hyperresponsiveness in ovalbumin-sensitized BALB/c mice.

  • 2014-06-17
  • PloS one 9(6)
  • • Yen-Wenn Liu
    • Tan-Wei Liao
    • Yu-Han Chen
    • Yi-Chin Chiang
    • Ying-Chieh Tsai

  • PubMed: 24936861
  • DOI: 10.1371/journal.pone.0100105

  3 Insights on

  • Reduced Airway Hyperresponsiveness

  • Low evidence
  • Animal Study

  The results showed that K37 dose-dependently lowered the serum levels of IgE, OVA-specific IgE and OVA-specific IgG1, ameliorated AHR induced by methacholine and suppressed eosinophil infiltration in bronchoalveolar lavage fluid (BALF).

  Effect

  Beneficial

  Effect size

  Large