Lactobacillus brevis SBC8803 and Reduced Hepatic Fat Accumulation

• Effect of probiotics Lactobacillus paracasei GKS6, L. plantarum GKM3, and L. rhamnosus GKLC1 on alleviating alcohol-induced alcoholic liver disease in a mouse model.

  • 2020-09-28
  • Clinical Trial · n = 6
  • Nutrition research and practice 14(4)
  • • You-Shan Tsai
    • Shih-Wei Lin
    • Yen-Lien Chen
    • Chin-Chu Chen

  • PubMed: 32765811
  • DOI: 10.4162/nrp.2020.14.4.299

  5 Insights on

  • Reduced Hepatic Fat Accumulation

  • Moderate evidence

  The histopathological results showed that all probiotics could reduce the accumulation of liver fat.

  Effect

  Beneficial

  Effect size

  Moderate

• Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates alcoholic liver disease in ethanol-containing diet-fed C57BL/6N mice.

  • 2008-12
  • Clinical Trial
  • International Journal of Food Microbiology 128(2)
  • • S. Segawa
    • Yoshihisa Wakita
    • H. Hirata
    • J. Watari

  • PubMed: 18976829
  • DOI: 10.1016/j.ijfoodmicro.2008.09.023

  22 Insights on

  • Reduced Hepatic Fat Accumulation

  • Low evidence
  • Highly Cited
  • Animal Study

  Oral administration of L. brevis significantly inhibited an increase in... the content of TG and total cholesterol in the liver caused by ethanol intake.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes