Lactobacillus brevis SBC8803 and Reduced Intestinal Permeability

• Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders.

  • 2015-10-14
  • Review
  • Frontiers in cellular neuroscience 9
  • • John R Kelly
    • Paul J Kennedy
    • John F Cryan
    • Timothy G Dinan
    • Gerard Clarke
    • Niall P Hyland

  • PubMed: 26528128
  • DOI: 10.3389/fncel.2015.00392

  3 Insights on

  • Reduced Intestinal Permeability

  • Moderate evidence
  • Highly Cited

  the concept that a "leaky gut" may facilitate communication between the microbiota and these key signaling pathways has gained traction.

  Effect

  Beneficial

  Effect size

  Small

• Targeting the gut barrier for the treatment of alcoholic liver disease.

  • 2017-12
  • Review
  • Liver research (Beijing, China) 1(4)
  • • Zhanxiang Zhou
    • Wei Zhong

  • PubMed: 30034913
  • DOI: 10.1016/j.livres.2017.12.004

  4 Insights on

  • Reduced Intestinal Permeability

  • Low evidence

  Alcohol consumption disrupts the gut barrier, increases gut permeability, and induces bacterial translocation... Potential strategies aimed at restoring the gut barrier in ALD.

  Effect

  Beneficial

  Effect size

  Moderate