Lactobacillus brevis VPro 18 and Increased Antibacterial Activity

• A Newly Characterized Potentially Probiotic Strain, Lactobacillus brevis MK05, and the Toxicity Effects of its Secretory Proteins Against MCF-7 Breast Cancer Cells

  • 2021-03-09
  • Probiotics and Antimicrobial Proteins 13(4)
  • • Mona Pourbaferani
    • Sima Modiri
    • A. Norouzy
    • H. Maleki
    • Mohadeseh Heidari
    • L. Alidoust
    • Venus Derakhshan
    • H. Zahiri
    • K. A. Noghabi

  • PubMed: 33687634
  • DOI: 10.1007/s12602-021-09766-8

  3 Insights on

  • Increased Antibacterial Activity

  • Low evidence
  • Clinical

  The collected cell-free supernatant (CFC) of L. brevis MK05 culture, compared with MRS broth with pH equal to the pH for CFC, revealed antimicrobial activity against Escherichia coli (ATCC 25922) and Staphylococcus aureus subsp. aureus (ATCC 25923), possibly due to the presence of antibacterial metabolites other than organic acids.

  Effect

  Beneficial

  Effect size

  Moderate