Lactobacillus casei HA-108 and Improved Antiviral Immune Response

• Identification of immunomodulating properties of postbiotics from lactobacilli using the zebrafish (Danio rerio) model.

  • 2025-11-28
  • n = 330
  • BMC veterinary research 22(1)
  • • Chamilani Nikapitiya
    • Jayasinghage Nirmani Chathurangika Jayasinghe
    • Mawalle Kankanamge Hasitha Madhawa Dias
    • E H T Thulshan Jayathilaka
    • Shan Lakmal Edirisinghe
    • Cheol- Hee Kim
    • Marion Schiavone
    • Eric Leclercq
    • Emmanuelle Apper
    • Amélie Mugnier
    • Mahanama De Zoysa

  • PubMed: 41316341
  • DOI: 10.1186/s12917-025-05159-z

  2 Insights on

  • Improved Antiviral Immune Response

  • Low evidence
  • Animal Study

  All postbiotics treatments modulated immune responses, with L. plantarum HA-119 showing the most pronounced effects... Survival rates were significantly higher in the L. plantarum HA-119 and L. helveticus HA-122 groups compared to the VHSV control.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes