Lactobacillus casei Lc-11 and Enhanced Mucosal Immune Response

• Engineered Lactobacillus casei targets the IgT-pIgR axis to confer mucosal protection against Aeromonas veronii in snakehead (Channa argus).

  • 2026-03-23
  • Frontiers in immunology 17
  • • Kui-Peng Gao
    • Jian-Ran Dou
    • Bing-Bing Ma
    • Tian-Bao Ma
    • Na Li
    • Ai-Dong Qian
    • Xiao-Feng Shan
    • Wu-Wen Sun
    • Lei Zhang
    • Di Zhang
    • Chun-Feng Wang
    • Dong-Xing Zhang

  • PubMed: 41948342
  • DOI: 10.3389/fimmu.2026.1759765

  3 Insights on

  • Enhanced Mucosal Immune Response

  • Low evidence
  • Animal Study

  The probiotic treatment accelerated pathogen clearance, improved survival rates to 42.9% compared to 12.5% in control group, and reorganized the commensal microbiome

  Effect

  Beneficial

  Effect size

  Large