Lactobacillus casei rhamnosus and Improved Oral Retention

• Preparation and characterization of Lactobacillus rhamnosus, Lactobacillus casei, glycyrrhizin, vitamin-D3, and citric acid-loaded mucoadhesive pectin microparticles for the management of dental caries.

  • 2025-11-27
  • BMC pharmacology & toxicology 26(1)
  • • Sumita Mishra
    • Somnath Ghosh
    • Koushik Jana
    • Biplab Debnath
    • Sudhanshu Ranjan Rout
    • Vineet Kumar Rai
    • Rakesh Kumar Sahoo
    • Jitu Halder
    • Ritu Mahanty
    • Priyanka Dash
    • Chandan Das
    • Salim Manoharadas
    • Jameel Al-Tamimi
    • Muralidhar Tata
    • Neeta Mohanty
    • Biswakanth Kar
    • Goutam Ghosh
    • Goutam Rath

  • PubMed: 41310863
  • DOI: 10.1186/s40360-025-01010-1

  4 Insights on

  • Improved Oral Retention

  • Low evidence

  In vivo studies on Wistar rats confirmed prolonged retention in the oral cavity and effective antimicrobial and anti-inflammatory activity

  Effect

  Beneficial

  Effect size

  Moderate