Lactobacillus crispatus LV5 and Absence of Deep Epithelial Disruption

• Phase 2a Study Assessing Colonization Efficiency, Safety, and Acceptability of Lactobacillus crispatus CTV-05 in Women With Bacterial Vaginosis

  • 2010-12
  • RCT · n = 24
  • Sexually Transmitted Diseases 37(12)
  • • A. Hemmerling
    • William G. Harrison
    • A. Schroeder
    • Je-Bok Park
    • A. Korn
    • S. Shiboski
    • A. Foster-Rosales
    • C. Cohen

  • PubMed: 20644497
  • DOI: 10.1097/OLQ.0b013e3181e50026

  11 Insights on

  • Absence of Deep Epithelial Disruption

  • High evidence
  • Highly Cited

  No grade 3 or 4 AEs or serious AEs occurred and no deep epithelial disruption was seen during colposcopic evaluation.

  Effect

  Beneficial

  Effect size

  Moderate