Local Probiotic Lactobacillus crispatus and Lactobacillus delbrueckii Exhibit Strong Antifungal Effects Against Vulvovaginal Candidiasis in a Rat Model
- 2019-05-08
- Clinical Trial
- Frontiers in Microbiology 10
- Ting Li
- Zhaohui Liu
- Xu Zhang
- Xi Chen
- Su-xia Wang
- PubMed: 31139166
- DOI: 10.3389/fmicb.2019.01033
- Low evidence
- Animal Study
Our results indicated that Lactobacillus administration played an indispensable role in maintaining the immune homeostasis, and decreasing the Th1/Th2 ratio (IFN-γ/IL-4) by regulating the epithelial secretion of cytokines that inhibit epithelial proinflammatory cytokine release.
- Beneficial
- Moderate effect