Lactobacillus crispatus LV5 and Reduced Atopobium spp. Concentration

• Effects of Bacterial Vaginosis-Associated Bacteria and Sexual Intercourse on Vaginal Colonization With the Probiotic Lactobacillus crispatus CTV-05

  • 2011-11
  • RCT · n = 24
  • Sexually Transmitted Diseases 38(11)
  • • B. Ngugi
    • A. Hemmerling
    • E. Bukusi
    • G. Kikuvi
    • J. Gikunju
    • S. Shiboski
    • D. Fredricks
    • C. Cohen

  • PubMed: 21992977
  • DOI: 10.1097/OLQ.0b013e3182267ac4

  10 Insights on

  • Reduced Atopobium spp. Concentration

  • High evidence

  Similarly, the median concentration of Atopobium spp. reduced from 10 16S rRNA gene copies per swab to below limit of detection in women who colonized with CTV-05.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes