Lactobacillus crispatus LV5 and Reduced Detection of Cervical Intraepithelial Neoplasia

• Associations of cervicovaginal lactobacilli with high-risk HPV infection, cervical intraepithelial neoplasia, and cancer: a systematic review and meta-analysis.

  • 2019-06-27
  • Meta-Analysis
  • The Journal of Infectious Diseases 220(8)
  • • Huiyan Wang
    • Yan Ma
    • Ruonan Li
    • Xixi Chen
    • Lijuan Wan
    • Weidong Zhao

  • PubMed: 31242505
  • DOI: 10.1093/infdis/jiz325

  2 Insights on

  • Reduced Detection of Cervical Intraepithelial Neoplasia

  • High evidence
  • Rigorous Journal

  Lactobacillus crispatus... was correlated with the decreased detection of... CIN (OR = 0.50, 95% CI = 0.29-0.88, I2 = 0%)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes