Lactobacillus crispatus LV5 and Reduced Expression of Hyphae-specific Genes

• Antimicrobial Compounds Produced by Vaginal Lactobacillus crispatus Are Able to Strongly Inhibit Candida albicans Growth, Hyphal Formation and Regulate Virulence-related Gene Expressions

  • 2017-04-04
  • Frontiers in Microbiology 8
  • • Shuai Wang
    • Qiangyi Wang
    • E. Yang
    • Ling Yan
    • Tong Li
    • Zhuang Hui

  • PubMed: 28421058
  • DOI: 10.3389/fmicb.2017.00564

  6 Insights on

  • Reduced Expression of Hyphae-specific Genes

  • Low evidence
  • Highly Cited

  The results demonstrated that *L. crispatus* CFS significantly down-regulated the expression of hyphae-specific genes *ALS3* (0.140-fold), *HWP1* (0.075-fold), and *ECE1* (0.045-fold).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes