Lactobacillus crispatus LV5 and Reduced Interleukin-1β Levels

• Lactobacillus crispatus modulates epithelial cell defense against Candida albicans through Toll-like receptors 2 and 4, interleukin 8 and human β-defensins 2 and 3.

  • 2013-11
  • Immunology Letters 156(1-2)
  • • A. Rizzo
    • A. Losacco
    • C. Carratelli

  • PubMed: 24120511
  • DOI: 10.1016/j.imlet.2013.08.013

  3 Insights on

  • Reduced Interleukin-1β Levels

  • Low evidence
  • Highly Cited

  When HeLa cells were pre-treated with the L. crispatus and infected with C. albicans, the interleukin-8 levels were significantly lower than without pre-treatment.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes