Lactobacillus crispatus VPro 31 and Non-toxicity to Cervicovaginal Epithelial Cells

• S-layer protein 2 of Lactobacillus crispatus 2029, its structural and immunomodulatory characteristics and roles in protective potential of the whole bacteria against foodborne pathogens.

  • 2020-05
  • International Journal of Biological Macromolecules 150
  • • V. Abramov
    • I. Kosarev
    • T. Priputnevich
    • A. Machulin
    • V. Khlebnikov
    • S. Pchelintsev
    • R. Vasilenko
    • V. Sakulin
    • N. Suzina
    • I. Chikileva
    • Evgenia I Derysheva
    • V. Melnikov
    • I. N. Nikonov
    • V. A. Samoilenko
    • Eduard E Svetoch
    • G. Sukhikh
    • V. Uversky
    • A. V. Karlyshev

  • PubMed: 32045605
  • DOI: 10.1016/j.ijbiomac.2020.02.065

  16 Insights on

  • Non-toxicity to Cervicovaginal Epithelial Cells

  • Low evidence

  No toxicity to or damage of Caco-2 or HT-29 epithelial cells were detected after 24 h of colonization by LC2029 lactobacilli.

  Effect

  Beneficial

  Effect size

  Moderate

• Probiotic Properties of Lactobacillus crispatus 2,029: Homeostatic Interaction with Cervicovaginal Epithelial Cells and Antagonistic Activity to Genitourinary Pathogens

  • 2014-07-16
  • Probiotics and Antimicrobial Proteins 6(3-4)
  • • V. Abramov
    • V. Khlebnikov
    • I. Kosarev
    • Guldana Bairamova
    • R. Vasilenko
    • N. Suzina
    • A. Machulin
    • V. Sakulin
    • N. Kulikova
    • Nadezhda F. Vasilenko
    • A. V. Karlyshev
    • V. Uversky
    • M. Chikindas
    • V. Melnikov

  • PubMed: 25028263
  • DOI: 10.1007/s12602-014-9164-4

  15 Insights on

  • Non-toxicity to Cervicovaginal Epithelial Cells

  • Low evidence

  There were no toxicity, epithelial damage and apoptosis after 24 h of colonization.

  Effect

  Neutral

  Effect size

  Moderate