Lactobacillus delbrueckii VPro 315 and Reduced Intestinal Oxidative Damage

• Lactobacillus delbrueckii Protected Intestinal Integrity, Alleviated Intestinal Oxidative Damage, and Activated Toll-Like Receptor–Bruton’s Tyrosine Kinase–Nuclear Factor Erythroid 2-Related Factor 2 Pathway in Weaned Piglets Challenged with Lipopolysaccharide

  • 2021-03-16
  • RCT · n = 36
  • Antioxidants 10(3)
  • • Fengming Chen
    • Jiayi Chen
    • Qinghua Chen
    • Lingyuan Yang
    • J. Yin
    • Yinghui Li
    • Xingguo Huang

  • PubMed: 33809627
  • DOI: 10.3390/antiox10030468

  3 Insights on

  • Reduced Intestinal Oxidative Damage

  • Low evidence
  • Rigorous Journal
  • Animal Study

  LAB supplementation normalized other LPS-induced changes, such as by decreasing malondialdehyde (MDA) in both the serum and intestinal mucosa and 8-hydroxy-2-deoxyguanosine (8-OHdG) in the jejunal mucosa.

  Effect

  Beneficial

  Effect size

  Moderate