Lactobacillus delbrueckii and Reduced Sleep Disturbance Score

• Topical probiotic Lactobacillus lactis treatment in atopic dermatitis: a placebo-controlled pilot study on tolerability and efficacy.

  • 2026-02-03
  • Clinical Trial · n = 13
  • Frontiers in medicine 13
  • • Ville Salo
    • Anita Remitz
    • Antti Lauerma
    • Alexander Salava

  • PubMed: 41709889
  • DOI: 10.3389/fmed.2026.1694229

  8 Insights on

  • Reduced Sleep Disturbance Score

  • Moderate evidence
  • Clinical

  sleep disturbance VAS, p = 1.00, CI: 0.79-1.00

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  3%, 10%, and 30% cream (probiotic lysate cream)