Lactobacillus fermentum CECT5716 and Reduced Lupus-Associated Renal Damage

• Lactobacillus fermentum CECT5716 prevents renal damage in the NZBWF1 mouse model of systemic lupus erythematosus.

  • 2021-05-28
  • RCT
  • Food & Function 11(6)
  • • Néstor de la Visitación
    • Iñaki Robles‐Vera
    • M. Toral
    • F. O’Valle
    • Javier Moleón
    • M. Gómez-Guzmán
    • M. Romero
    • Marcos Duarte
    • Manuel Calderón Sánchez
    • R. Jiménez
    • J. Duarte

  • PubMed: 32458936
  • DOI: 10.1039/d0fo00578a

  11 Insights on

  • Reduced Lupus-Associated Renal Damage

  • Low evidence
  • Animal Study

  LC40 treatment reduced the increased plasma anti-dsDNA, endotoxemia, and high blood pressure in NZBWF1 mice. In parallel, LC40 also prevented alterations in kidney function parameters... and kidney injury... The main histological features found in the kidneys of lupus mice... were also reduced by LC40.

  Effect

  Beneficial

  Effect size

  Large