Lactobacillus fermentum HA-179 and Reduced Uric Acid Levels

• Host-derived Lactobacillus plantarum alleviates hyperuricemia by improving gut microbial community and hydrolase-mediated degradation of purine nucleosides.

  • 2024-11-07
  • eLife 13
  • • Yang Fu
    • Xiao-Dan Luo
    • Jin-Ze Li
    • Qian-Yuan Mo
    • Xue Wang
    • Yue Zhao
    • You-Ming Zhang
    • Hao-Tong Luo
    • Dai-Yang Xia
    • Wei-Qing Ma
    • Jian-Ying Chen
    • Li-Hau Wang
    • Qiu-Yi Deng
    • Lukuyu Ben
    • Muhammad Kashif Saleemi
    • Xian-Zhi Jiang
    • Juan Chen
    • Kai Miao
    • Zhen-Ping Lin
    • Peng Zhang
    • Hui Ye
    • Qing-Yun Cao
    • Yong-Wen Zhu
    • Lin Yang
    • Qiang Tu
    • Wence Wang

  • PubMed: 39508089
  • DOI: 10.7554/elife.100068

  2 Insights on

  • Reduced Uric Acid Levels

  • Low evidence
  • Animal Study

  Oral administration of L. plantarum SQ001 resulted in increased abundance of Lactobacillus species and reduced serum UA levels.

  Effect

  Beneficial

  Effect size

  Moderate