Lactobacillus fermentum CQPC08 protects rats from lead-induced oxidative damage by regulating the Keap1/Nrf2/ARE pathway.
- 2021
- Clinical Trial
- Food & Function 12(13)
- X. Long
- F. Sun
- Zhiying Wang
- Tongjin Liu
- Jianjun Gong
- Xuemei Kan
- Yujie Zou
- Xin Zhao
- PubMed: 34037025
- DOI: 10.1039/d1fo00589h
- Low evidence
- Animal Study
LF-CQPC08 can also activate the Keap1/Nrf2/ARE signaling pathway to promote high-level expression of the downstream antioxidants heme oxygenase 1 (HO-1), NAD(P)H : quinone oxidoreductase 1 (NQO1), and γ-glutamylcysteine synthetase (γ-GCS).
- Effect
- Beneficial
- Effect size
- Large