Lactobacillus fermentum LF61 and Reduced Hepatic Oxidative Stress

• Lactobacillus fermentum CQPC08 protects rats from lead-induced oxidative damage by regulating the Keap1/Nrf2/ARE pathway.

  • 2021
  • Clinical Trial
  • Food & Function 12(13)
  • • X. Long
    • F. Sun
    • Zhiying Wang
    • Tongjin Liu
    • Jianjun Gong
    • Xuemei Kan
    • Yujie Zou
    • Xin Zhao

  • PubMed: 34037025
  • DOI: 10.1039/d1fo00589h

  8 Insights on

  • Reduced Hepatic Oxidative Stress

  • Low evidence
  • Animal Study

  LF-CQPC08 can reduce the proinflammatory factors interleukin (IL)-1 beta (1β), IL-6, tumor necrosis factor alpha, and interferon gamma in the body, increase the level of anti-inflammatory factor IL-10, enhance the activity of antioxidant enzymes such as superoxide dismutase and catalase and glutathione levels in serum and organ tissues, and reduce the production of reactive oxygen species and accumulation of lipid peroxide malondialdehyde.

  Effect

  Beneficial

  Effect size

  Large