Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress.
- 2016-03-11
- RCT · n = 47
- Beneficial Microbes 7(2)
- Akito Kato-Kataoka
- K. Nishida
- M. Takada
- K. Suda
- M. Kawai
- K. Shimizu
- Akira Kushiro
- R. Hoshi
- O. Watanabe
- Tomoki Igarashi
- K. Miyazaki
- Y. Kuwano
- K. Rokutan
- PubMed: 26689231
- DOI: 10.3920/BM2015.0100
- High evidence
- Highly Cited
In association with a significant elevation of anxiety at 1 day before the examination, salivary cortisol and plasma L-tryptophan levels were significantly increased in only the placebo group (P<0.05).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes