Lactobacillus fermentum MAK20L13F and Reduced Asymptomatic Bacterial Vaginosis

• Oral use of Lactobacillus rhamnosus GR-1 and L. fermentum RC-14 significantly alters vaginal flora: randomized, placebo-controlled trial in 64 healthy women.

  • 2003-03
  • RCT · n = 64
  • FEMS Immunology & Medical Microbiology 35(2)
  • • G. Reid
    • D. Charbonneau
    • J. Erb
    • B. Kochanowski
    • D. Beuerman
    • Russ Poehner
    • A. Bruce

  • PubMed: 12628548
  • DOI: 10.1016/S0928-8244(02)00465-0

  11 Insights on

  • Reduced Asymptomatic Bacterial Vaginosis

  • High evidence
  • Highly Cited

  Microscopy analysis showed restoration from asymptomatic bacterial vaginosis microflora to a normal lactobacilli colonized microflora in 37% women during lactobacilli treatment compared to 13% on placebo (P=0.02).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes