Fermented milk containing Lactobacillus casei strain Shirota prevents the onset of physical symptoms in medical students under academic examination stress.
- 2016-03-11
- RCT · n = 47
- Beneficial Microbes 7(2)
- Akito Kato-Kataoka
- K. Nishida
- M. Takada
- K. Suda
- M. Kawai
- K. Shimizu
- Akira Kushiro
- R. Hoshi
- O. Watanabe
- Tomoki Igarashi
- K. Miyazaki
- Y. Kuwano
- K. Rokutan
- PubMed: 26689231
- DOI: 10.3920/BM2015.0100
- High evidence
- Highly Cited
Moreover, the rate of subjects experiencing common abdominal and cold symptoms and total number of days experiencing these physical symptoms per subject were significantly lower in the LcS group than in the placebo group during the pre-examination period at 5-6 weeks (each P<0.05) and 7-8 weeks (each P<0.01) during the intervention period.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes