Lactobacillus gasseri LAC-343 and Improved Stress Tolerance

• Manipulating the growth environment through co-culture to enhance stress tolerance and viability of probiotic strains in the gastrointestinal tract.

  • 2023-12-21
  • Clinical Trial
  • Applied and environmental microbiology 89(12)
  • • Kosuke Oana
    • Kensuke Shimizu
    • Toshihiko Takada
    • Hiroshi Makino
    • Mikiko Yamazaki
    • Miyuki Katto
    • Minoru Ando
    • Takashi Kurakawa
    • Kenji Oishi

  • PubMed: 38019024
  • DOI: 10.1128/aem.01502-23

  1 Insight on

  • Improved Stress Tolerance

  • High evidence
  • Rigorous Journal

  use of co-culture or pH-controlled monoculture, which uses more stringent conditions (lower pH) than normal monoculture to produce probiotic strains that are more resistant to gastrointestinal stress.

  Effect

  Beneficial

  Effect size

  Moderate