Lactobacillus gasseri LG-36 and No Effect on Clostridioides difficile Colonization

• Differential modulation of post-antibiotic colonization resistance to Clostridioides difficile by two probiotic Lactobacillus strains.

  • 2025-08-13
  • mBio 16(8)
  • • Matthew H Foley
    • Arthur S McMillan
    • Sarah O'Flaherty
    • Rajani Thanissery
    • Molly E Vanhoy
    • Mary Gracen Fuller
    • Rodolphe Barrangou
    • Casey M Theriot

  • PubMed: 40689613
  • DOI: 10.1128/mbio.01468-25

  2 Insights on

  • No Effect on Clostridioides difficile Colonization

  • Low evidence
  • Rigorous Journal
  • Animal Study

  In contrast, <i>L. gasseri</i> decreased <i>C. difficile</i> and promoted the return of colonization resistance

  Effect

  Beneficial

  Effect size

  Moderate