Lactobacillus helveticus R0052 and Reduced Anxiety-Related Feeding Behavior

• Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 administration to Long-Evans rats has interactive effects with sex and diet on anxiety-related feeding behaviors and specific endocrine outcomes.

  • 2025-10
  • Physiology & behavior 300
  • • Elizabeth M Myles
    • M Elizabeth O'Leary
    • Isaac D Romkey
    • Sara I Hamm
    • Laura Dauphinee
    • Amanda Piano
    • Stéphane Bronner
    • Tara S Perrot

  • PubMed: 40664306
  • DOI: 10.1016/j.physbeh.2025.115030

  2 Insights on

  • Reduced Anxiety-Related Feeding Behavior

  • Low evidence
  • Animal Study

  In WD-fed rats, the probiotic attenuated the increase in daily calorie intake observed in placebo rats. Subsequently, in the novelty-suppressed feeding task (NSFT), probiotic standard diet (SD) males spent more time in the center of an open field, suggesting a reduced anxiety-related state.

  Effect

  Beneficial

  Effect size

  Small