Lactobacillus helveticus R0052 attenuates DSS-induced colitis via modulation of gut microbiota, intestinal metabolites and immunological profiles in a mouse model.
- 2025-11
- Microbial pathogenesis 208
- Xiangmin Dong
- Shengyi Han
- Hua Zha
- Lanjuan Li
- PubMed: 40849096
- DOI: 10.1016/j.micpath.2025.108002
- Low evidence
- Animal Study
The administration of LH R0052 exerted a protective effect against colitis by improving the phenotypic presentation... DSS administration induced significant body weight loss, colon shortening, and elevated disease activity index (DAI).
- Effect
- Beneficial
- Effect size
- Moderate