Lactobacillus helveticus Rosell-52 and Improved Cognitive Function

• Role of Probiotics in Management of Depressive Symptoms and Cognitive Impairment in Patients With Depression: An Updated Analysis of Trials.

  • 2025-11-29
  • Meta-Analysis
  • Brain and behavior 15(12)
  • • Syed Ali Arsal
    • Aashish Kumar
    • Umer Iqbal
    • Shafin Bin Amin
    • Muhammad Aniq Amir
    • Muhammad Abrar Amir
    • Muhammad Ashir Shafique
    • Suhaib Ahmed
    • Laksh Kumar
    • Oluwatobiloba Israel Popoola
    • Inibehe Ime Okon

  • PubMed: 41319022
  • DOI: 10.1002/brb3.71108

  2 Insights on

  • Improved Cognitive Function

  • High evidence

  Patients receiving probiotics had significant alleviation of cognitive symptoms (p = 0.01; SMD, -0.90; 95% confidence interval [CI], -1.59 to -0.21; I2 = 82%) in comparison to placebo

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Psychobiotics in mental health: insights from human clinical trials via the gut-brain axis.

  • 2026-03-27
  • Review
  • Frontiers in microbiology 17
  • • Natarajan Sisubalan
    • Periyanaina Kesika
    • Bhagavathi Sundaram Sivamaruthi
    • Chaiyavat Chaiyasut

  • PubMed: 41971341
  • DOI: 10.3389/fmicb.2026.1804560

  7 Insights on

  • Improved Cognitive Function

  • Low evidence

  While some studies reported improvements in mood, anxiety, sleep quality, and cognitive performance, others showed limited effects, particularly in healthy populations with low baseline stress levels

  Effect

  Beneficial

  Effect size

  Small

• Probiotic supplementation for optimizing athletic performance: current evidence and future perspectives for microbiome-based strategies.

  • 2025-07-15
  • Review
  • Frontiers in nutrition 12
  • • Timea Teglas
    • Zsolt Radak

  • PubMed: 40735239
  • DOI: 10.3389/fnut.2025.1572687

  10 Insights on

  • Improved Cognitive Function

  • Low evidence

  it appears that probiotics have a beneficial effect on mental health, cognitive functions, sleep, gastrointestinal, and upper respiratory symptoms in adult humans.

  Effect

  Beneficial

  Effect size

  Small