Lactobacillus helveticus VPro 13 and Reduced Autistic-Like Behavioral Symptoms

• Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation.

  • 2021-06-01
  • Clinical Trial
  • Food & Function 12(6)
  • • Qingmin Kong
    • Botao Wang
    • Peijun Tian
    • Xiu-xia Li
    • Jianxin Zhao
    • Hao Zhang
    • Wei Chen
    • Gang Wang

  • PubMed: 33629689
  • DOI: 10.1039/d0fo02375b

  5 Insights on

  • Reduced Autistic-Like Behavioral Symptoms

  • Low evidence
  • Animal Study

  While improving autistic-like behavioral symptoms, we found L. helveticus CCFM1076 was more beneficial in regulating 5HT anabolism and catabolism, balancing excitatory and inhibitory neurotransmitter release in the PNS and CNS, and increasing oxytocin (OT) synthesis in the hypothalamus.

  Effect

  Beneficial

  Effect size

  Moderate