Effects of Pro/Prebiotics Alone over Pro/Prebiotics Combined with Conventional Antibiotic Therapy to Treat Bacterial Vaginosis: A Systematic Review.
- 2022-01
- Systematic Review
- International journal of clinical practice 2022(1)
- Roghayeh Afifirad
- Amir Darb Emamie
- Rezvan Golmoradi Zadeh
- Parisa Asadollahi
- Roya Ghanavati
- Atieh Darbandi
- PubMed: 35685517
- DOI: 10.1155/2022/4774783
- High evidence
In studies comparing the effects of pre/probiotics and placebos with or without antibiotic therapy in patients with BV, significant differences in clinical outcomes were observed. Probiotics reduced the levels of IL-1β and IL-6, as well as the overall Nugent score and Amsel's criteria for restitution of a balanced vaginal microbiota.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes