Lactobacillus jensenii LBV 116 and Increased Abundance of Lactobacillus Crispatus

• Preterm-birth-prevention with Lactobacillus crispatus oral probiotics: Protocol for a double blinded randomised placebo-controlled trial (the PrePOP study).

  • 2025-02
  • RCT · n = 126
  • Contemporary clinical trials 149
  • • Gillian A Corbett
    • Siobhan Corcoran
    • Conor Feehily
    • Benedetta Soldati
    • Anthony Rafferty
    • David A MacIntyre
    • Paul D Cotter
    • Fionnuala M McAuliffe

  • PubMed: 39701375
  • DOI: 10.1016/j.cct.2024.107776

  2 Insights on

  • Increased Abundance of Lactobacillus Crispatus

  • High evidence
  • Large Human Trial

  The primary outcome is detectable L. crispatus in the vaginal microbiome after twelve weeks of treatment... to detect a 25 % increase in detectable L. crispatus.

  Effect

  Beneficial

  Effect size

  Small