Lactobacillus jensenii LJe52 and Reduced Risk of Chorioamnionitis

• Identification and H2O2 Production of Vaginal Lactobacilli from Pregnant Women at High Risk of Preterm Birth and Relation with Outcome

  • 2004-02
  • Observational
  • Journal of Clinical Microbiology 42(2)
  • • M. Wilks
    • R. Wiggins
    • A. Whiley
    • E. Hennessy
    • S. Warwick
    • H. Porter
    • A. Corfield
    • M. Millar

  • PubMed: 14766841
  • DOI: 10.1128/JCM.42.2.713-717.2004

  1 Insight on

  • Reduced Risk of Chorioamnionitis

  • Moderate evidence
  • Highly Cited

  We also report the correlation between identification and H(2)O(2) production in relation to the outcomes of chorioamnionitis and preterm birth.... We postulate that H(2)O(2)-producing lactobacilli are able to reduce the incidence of ascending infections of the uterus and the subsequent production of proinflammatory molecules which are important in the pathogenesis of chorioamnionitis and preterm birth.

  Effect

  Beneficial

  Effect size

  Moderate