Lactobacillus johnsonii LJ09 and Balanced T-Cell Differentiation

• Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response.

  • 2021-08
  • Cytokine 144
  • • D. Zheng
    • Zhaorui Wang
    • Ling Sui
    • Yigang Xu
    • Li Wang
    • X. Qiao
    • W. Cui
    • Yan-ping Jiang
    • Han Zhou
    • Lijie Tang
    • Yi-jing Li

  • PubMed: 34029942
  • DOI: 10.1016/j.cyto.2021.155581

  4 Insights on

  • Balanced T-Cell Differentiation

  • Low evidence

  MoDCs stimulated by L. johnsonii mainly promoted T cell differentiate into Th1/Th2/Treg cells and plays an important role in improving the balance between Th1/Th2/Treg-type cells, whereas MoDCs stimulated by L. johnsonii-CFS mainly directed T cell to Th2/Treg subset polarization.

  Effect

  Beneficial

  Effect size

  Moderate