Lactobacillus johnsonii activates porcine monocyte derived dendritic cells maturation to modulate Th cellular immune response.
- 2021-08
- Cytokine 144
- D. Zheng
- Zhaorui Wang
- Ling Sui
- Yigang Xu
- Li Wang
- X. Qiao
- W. Cui
- Yan-ping Jiang
- Han Zhou
- Lijie Tang
- Yi-jing Li
- PubMed: 34029942
- DOI: 10.1016/j.cyto.2021.155581
- Low evidence
Analysis of the cytokines showed that L. johnsonii stimulated up-regulation of Th1-type cytokines (IL-12p40, IFN-γ, TNF-α), pro-inflammatory cytokine IL-1β, chemokine CCL20, and Treg-type / anti-inflammatory cytokines IL-10 in MoDCs.
- Effect
- Beneficial
- Effect size
- Moderate