Lactobacillus johnsonii LJ09 and Reduced Alcohol-Induced Liver Injury

• Heat-Killed Lactobacillus salivarius and Lactobacillus johnsonii Reduce Liver Injury Induced by Alcohol In Vitro and In Vivo

  • 2016-10-31
  • Molecules 21(11)
  • • C. Chuang
    • Cheng-Chih Tsai
    • E. Lin
    • Chin-Shiu Huang
    • Yun-Yu Lin
    • Chuan-Ching Lan
    • Chun-Chih Huang

  • PubMed: 27809254
  • DOI: 10.3390/MOLECULES21111456

  3 Insights on

  • Reduced Alcohol-Induced Liver Injury

  • Low evidence

  The aim of the present study was to determine whether Lactobacillus salivarius (LS) and Lactobacillus johnsonii (LJ) prevent alcoholic liver damage in HepG2 cells and rat models of acute alcohol exposure. Our results indicated that heat-killed LS and LJ reduced AST, ALT, γ-GT and malondialdehyde (MDA) levels and outperformed other bacterial strains in cell line studies.

  Effect

  Beneficial

  Effect size

  Moderate