Lactobacillus johnsonii LJ09 and Reduced Colitis-Related Mortality

• L. pseudomesenteroides and L. johnsonii isolated from yaks in Tibet modulate gut microbiota in mice to ameliorate enteroinvasive Escherichia coli-induced diarrhea.

  • 2019-07
  • RCT · n = 40
  • Microbial Pathogenesis 132
  • • Yaping Wang
    • Aoyun Li
    • Juan-juan Liu
    • K. Mehmood
    • Basang Wangdui
    • Hongmei Shi
    • Xiaolin Luo
    • Hui Zhang
    • Jia-kui Li

  • PubMed: 30999021
  • DOI: 10.1016/j.micpath.2019.04.020

  4 Insights on

  • Reduced Colitis-Related Mortality

  • Low evidence
  • Animal Study

  After two days, the mice in control group were recorded for high mortality. The diarrhea in LP1 and LJ1 groups was much lower than that in the control group, and no death was recorded.

  Effect

  Beneficial

  Effect size

  Large