Lactobacillus johnsonii LJ09 and Reduced Organ Damage

• L. pseudomesenteroides and L. johnsonii isolated from yaks in Tibet modulate gut microbiota in mice to ameliorate enteroinvasive Escherichia coli-induced diarrhea.

  • 2019-07
  • RCT · n = 40
  • Microbial Pathogenesis 132
  • • Yaping Wang
    • Aoyun Li
    • Juan-juan Liu
    • K. Mehmood
    • Basang Wangdui
    • Hongmei Shi
    • Xiaolin Luo
    • Hui Zhang
    • Jia-kui Li

  • PubMed: 30999021
  • DOI: 10.1016/j.micpath.2019.04.020

  4 Insights on

  • Reduced Organ Damage

  • Low evidence
  • Animal Study

  In histopathology, pre-supplementation of LJ1 and LP1 relieved the damage to the liver, spleen and duodenum caused by E. coli.

  Effect

  Beneficial

  Effect size

  Large