Lactobacillus johnsonii VPro 33 and Altered CD4+ T-cell Cytokine Levels

• Lactobacillus johnsonii Supplementation Attenuates Respiratory Viral Infection via Metabolic Reprogramming and Immune Cell Modulation

  • 2017-11
  • Clinical Trial
  • Mucosal Immunology 10(6)
  • • W. Fonseca
    • Kaitlyn S. Lucey
    • Sihyug Jang
    • K. Fujimura
    • A. Rasky
    • Hung-An Ting
    • J. Petersen
    • C. Johnson
    • H. Boushey
    • E. Zoratti
    • D. Ownby
    • A. M. Levine
    • Kevin R. Bobbit
    • S. Lynch
    • N. Lukacs

  • PubMed: 28295020
  • DOI: 10.1038/mi.2017.13

  6 Insights on

  • Altered CD4+ T-cell Cytokine Levels

  • Low evidence
  • Rigorous Journal
  • Animal Study

  RSV-infected bone marrow-derived DCs (BMDCs) from L. johnsonii-supplemented mice had...modified CD4+ T-cell cytokines.

  Effect

  Beneficial

  Effect size

  Moderate