Lactobacillus johnsonii VPro 33 and Reduced Pathogenic Load

• Lactobacillus johnsonii L531 reduces pathogen load and helps maintain short-chain fatty acid levels in the intestines of pigs challenged with Salmonella enterica Infantis.

  • 2019-03
  • Clinical Trial
  • Veterinary Microbiology 230
  • • Ting He
    • Yaohong Zhu
    • Jiao Yu
    • B. Xia
    • Xiao Liu
    • Gui-Yan Yang
    • Jinhui Su
    • Liang Guo
    • Mengling Wang
    • Jiufeng Wang

  • PubMed: 30827387
  • DOI: 10.1016/j.vetmic.2019.02.003

  7 Insights on

  • Reduced Pathogenic Load

  • Low evidence
  • Animal Study

  Oral administration of L. johnsonii L531 to newly weaned piglets significantly decreased levels of Salmonella colonization in colonic and jejunal contents, accelerated the clearance of Salmonella in feces after infection, and reduced S. Infantis translocation to the spleen.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes