Lactobacillus kefiri and Increased Immune System Activation

• Immunostimulation by Lactobacillus kefiri S-layer proteins with distinct glycosylation patterns requires different lectin partners.

  • 2020-10
  • The Journal of biological chemistry 295(42)
  • • Mariano Malamud
    • Gustavo J Cavallero
    • Adriana C Casabuono
    • Bernd Lepenies
    • María de Los Ángeles Serradell
    • Alicia S Couto

  • PubMed: 32817316
  • DOI: 10.1074/jbc.ra120.013934

  1 Insight on

  • Increased Immune System Activation

  • Low evidence
  • Animal Study

  SLP-8321 and SLP-5818 have a similar effect regardless of the differences in their glycosylation patterns... the immunostimulatory activity of SLP-8321 depends on its recognition by Mincle... SLP-5818's effects are dependent on SignR3

  Effect

  Beneficial

  Effect size

  Moderate