Lactobacillus lactis LI-23 and Reduced Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis

• Current Evidence from Animal Models on Molecular Changes Underlying Antidepressant Effects of Psychobiotics.

  • 2026-01-22
  • Review
  • Pharmaceutics 18(1)
  • • Nevena Todorović Vukotić
    • Neda Đorđević
    • Andrijana Stanisavljević Ilić
    • Svetlana Soković Bajić
    • Ivana Perić

  • PubMed: 41599247
  • DOI: 10.3390/pharmaceutics18010140

  8 Insights on

  • Reduced Hyperactivity of the Hypothalamic-Pituitary-Adrenal Axis

  • Low evidence

  psychobiotics normalize the activity of the HPA axis

  Effect

  Beneficial

  Effect size

  Moderate