Lactobacillus lactis LI-23 and Reduced Offspring Eczema Risk

• Maternal probiotic supplementation and offspring health: an umbrella review with re-analysis of systematic reviews and meta-analyses.

  • 2026-03-26
  • Systematic Review
  • Frontiers in nutrition 13
  • • Wenrui Sun
    • Yu Cao
    • Shumin Li
    • Liping Sun
    • Yuexia Liao

  • PubMed: 41971379
  • DOI: 10.3389/fnut.2026.1764109

  2 Insights on

  • Reduced Offspring Eczema Risk

  • High evidence

  Maternal probiotic supplementation was associated with lower risks of eczema or atopic eczema in offspring, primarily within the first 1-2 years of life (e.g., RR = 0.52, 95% CI: 0.38 to 0.72; p < 0.001).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes