The effect of probiotic supplementation on episiotomy wound healing among primiparous women: a triple-blind randomized clinical trial.
- 2023-05-05
- RCT
- BMC complementary medicine and therapies 23(1)
- Derakhshan Abdollahpour
- Aziz Homayouni-Rad
- Roghaiyeh Nourizadeh
- Sevil Hakimi
- Esmat Mehrabi
- PubMed: 37147630
- DOI: 10.1186/s12906-023-03980-3
- High evidence
- Clinical
The mean (SD) score of wound healing in the probiotic group altered from 4.91(1.86) before discharge to 1.55 (0.99) during 5±1 days after birth and reached to 0.95 (0.27) during 15±1 days after birth. Further, the mean (SD) score of wound healing in the placebo group altered from 4.62 (1.99) before discharge to 2.80 (1.20) during 5±1 days after birth and reached to 1.45(0.71) during 15±1 days after birth (adjusted mean difference: -0.50, confidence interval 95%: -0.96 to -0.05, P=0.03).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- 1.5 * 10^9 colony-forming unit /capsule once a day