Lactobacillus paracasei 431 and Reduced Depression Score

• The effect of Lactobacillus casei on postpartum depression: a randomized controlled trial.

  • 2025-11-29
  • RCT
  • BMC psychiatry 26(1)
  • • Derakhshan Abdollahpour
    • Aziz Homayouni-Rad
    • Roghaiyeh Nourizadeh
    • Sevil Hakimi
    • Esmat Mehrabi

  • PubMed: 41318456
  • DOI: 10.1186/s12888-025-07658-7

  2 Insights on

  • Reduced Depression Score

  • High evidence

  No significant difference was observed between the groups (Mean Difference: -1.68, 95% CI: 0.08 to -2.56 to, p = 0.71).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  500 mg of capsules containing Lactobacillus casei 431 at a dose of 1.5 × 10^9 cfu/ml once daily