Lactobacillus paracasei LP-20 and Absence of Genotoxicity

• Safety studies of LP20 powder produced from heat-killed Lactobacillus plantarum L-137.

  • 2009-08
  • Clinical Trial
  • Regulatory Toxicology and Pharmacology 54(3)
  • • Y. Hirose
    • S. Murosaki
    • Y. Yamamoto
    • K. Muroyama
    • Y. Miwa
    • A. Fujishima
    • B. Lynch

  • PubMed: 19328216
  • DOI: 10.1016/j.yrtph.2009.03.007

  2 Insights on

  • Absence of Genotoxicity

  • Low evidence
  • Animal Study

  There was no evidence of genotoxicity of LP20 in the Ames assay (0-5000microg/plate) or in the in vitro chromosome aberration assay with Chinese hamster lung fibroblasts (0-5000microg/mL).

  Effect

  Neutral

  Effect size

  Large