The antibody response of vitamin A-deficient rats to pneumococcal polysaccharide is enhanced through coimmunization with lipopolysaccharide.
- 1994-02-01
- Clinical Trial
- Journal of Infectious Diseases 169(2)
- A. Pasatiempo
- M. Kinoshita
- D. T. Foulke
- A. Ross
- PubMed: 8106780
- DOI: 10.1093/INFDIS/169.2.441
- Low evidence
- Animal Study
Doses of 2 and 20 micrograms of LPS, but not 0.1 and 0.5 micrograms, produced significant adjuvanticity.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes