Lactobacillus paracasei LP-20 and Reduced Interleukin-6 Production

• Orally administered LPS enhances head kidney macrophage activation with down-regulation of IL-6 in common carp (Cyprinus carpio).

  • 2013-06
  • Clinical Trial
  • Fish & Shellfish Immunology 34(6)
  • • T. Kadowaki
    • Y. Yasui
    • Osamu Nishimiya
    • Y. Takahashi
    • C. Kohchi
    • G. Soma
    • H. Inagawa

  • PubMed: 23567856
  • DOI: 10.1016/j.fsi.2013.03.372

  1 Insight on

  • Reduced Interleukin-6 Production

  • Low evidence
  • Animal Study

  Orally administered LPS augmented the expression of interleukin (IL)-1β and TNF-α mRNAs but reduced the expression of IL-6 mRNA in head kidney.

  Effect

  Beneficial

  Effect size

  Moderate