Lactobacillus paracasei MCC1849 and No Measurable IFN-Alpha Induction

• Lactococcus lactis Strain Plasma Uniquely Induces IFN-α Production via Plasmacytoid Dendritic Cell Activation: A Comparative Study of Postbiotic Products.

  • 2025-09-26
  • n = 19
  • Microorganisms 13(10)
  • • Shigeru Fujimura
    • Masato Kawamura
    • Yurina Tamura

  • PubMed: 41156721
  • DOI: 10.3390/microorganisms13102261

  4 Insights on

  • No Measurable IFN-Alpha Induction

  • Low evidence

  This effect was not observed with other strains, even at higher bacterial loads (up to 1 × 10^11 cells). Z-stack imaging confirmed that LC-Plasma was actively phagocytosed by pDCs, whereas other strains, such as L. paracasei MCC1849, adhered to the cell surface without internalization.

  Effect

  Neutral

  Effect size

  Small