Lactobacillus paracasei VPro 224 and No Improvement in IBS Symptoms

• Effect of Lactobacillus paracasei CNCM I-1572 on symptoms, gut microbiota, short chain fatty acids, and immune activation in patients with irritable bowel syndrome: A pilot randomized clinical trial

  • 2018-05
  • RCT · n = 40
  • United European Gastroenterology Journal 6(4)
  • • C. Cremon
    • S. Guglielmetti
    • G. Gargari
    • Valentina Taverniti
    • A. Castellazzi
    • C. Valsecchi
    • C. Tagliacarne
    • W. Fiore
    • M. Bellini
    • L. Bertani
    • D. Gambaccini
    • M. Cicala
    • B. Germanà
    • M. Vecchi
    • I. Pagano
    • M. Barbaro
    • L. Bellacosa
    • V. Stanghellini
    • G. Barbara

  • PubMed: 29881616
  • DOI: 10.1177/2050640617736478

  7 Insights on

  • No Improvement in IBS Symptoms

  • High evidence
  • Highly Cited
  • Rigorous Journal

  *Lactobacillus paracasei* CNCM I-1572 did not significantly improve IBS symptoms, including primary efficacy variables worst abdominal pain/discomfort and IBS degree of relief

  Effect

  Neutral

  Effect size

  Small

  Significant

  No